A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) That is Persistent or Recurrent Following BCG Induction
MK-3475-676
NCT03711032
 Recruiting
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CIUSSS DE L'EST-DE-L'ILE-DE-MONTREAL
PAV. MAISONNEUVE/PAV. MARCEL-LAMOUREUX
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Bladder/urothelial |
Dr. Nawar Hanna
Leïla Idrissi Kaïtouni
514-252-3400 poste 5853
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A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) That is Persistent or Recurrent Following BCG Induction
MK-3475-676
NCT03711032
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Bladder/urothelial |
Dr. Yves Fradet
Pascale Lévesque-Bernier
418-525-4444 poste 16860
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A Phase 3, Randomized, Double-blind Study to Compare the Efficacy and Safety of Pembrolizumab in Combination With Lenvatinib Versus Pembrolizumab and Placebo as First Line Treatment for Locally Advanced or Metastatic Urothelial Carcinoma in Cisplatin-ineligible Participants Whose Tumors Express PD-L1, and in Participants Ineligible for Any Platinum-containing Chemotherapy Regardless of PD-L1 Expression
MK-7902-011 (LEAP-011)
NCT03898180
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Bladder/urothelial |
Dr. Yves Fradet
Marilyn Savard
418-525-4444 poste 20414
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A Phase II Randomized Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer
BicaBCa
NCT05327647
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Bladder/urothelial |
Dr. Paul Toren
Marilyn Savard
418-525-4444 poste 20414
|
A Phase 3, Multi-center, Randomized Study Evaluating Efficacy of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-Invasive Urothelial Carcinoma (MIBC) of the Bladder Who Are Not Receiving Radical Cystectomy
SunRISe-2
NCT04658862
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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Bladder/urothelial |
Dr. Louis Lacombe
Marilyn Savard
418-525-4444 poste 20414
|
A Phase III Randomized, Open-Label, Multicenter Study to Determine the Efficacy and Safety of Durvalumab in Combination With Tremelimumab and Enfortumab Vedotin or Durvalumab in Combination With Enfortumab Vedotin for Perioperative Treatment in Patients Ineligible for Cisplatin or Who Refuse Cisplatin Undergoing Radical Cystectomy for Muscle Invasive Bladder Cancer
VOLGA
NCT04960709
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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Bladder/urothelial |
Dr. Vincent Castonguay
Marilyn Savard
418-525-4444 poste 67703
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A Phase II Clinical Trial to Study the Efficacy and Safety of Pembrolizumab in Subjects With High Risk Non-muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy
MK-3475-057/KEYNOTE-057
NCT02625961
Recruiting
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
|
Bladder/urothelial |
Dr. Michele Lodde
Marilyn Savard
418-525-4444 poste 67703
|
A Phase 3 Randomized Study of Cystectomy Plus Perioperative Pembrolizumab Versus Cystectomy Alone in Cisplatin-ineligible Participants With Muscle-invasive Bladder Cancer
MK-3475-905 (KEYNOTE-905)
NCT03924895
Recruiting
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CIUSSS DU CENTRE-OUEST-DE-L'ILE-DE-MONTREAL
HOPITAL GENERAL JUIF SIR MORTIMER B.DAVIS
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Bladder/urothelial |
Dr. Maurice Anidjar
Oleg Loutochin
514-340-8222 poste 21627
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A Phase II Clinical Trial to Study the Efficacy and Safety of Pembrolizumab in Subjects With High Risk Non-muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy
MK-3475-057/KEYNOTE-057
NCT02625961
Recruiting
|
CIUSSS DE L'EST-DE-L'ILE-DE-MONTREAL
PAV. MAISONNEUVE/PAV. MARCEL-LAMOUREUX
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Bladder/urothelial |
Dr. Nawar Hanna
Samara Bloom
514-252-3400 poste 6244
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Canadian Bladder Cancer Information System (CBCIS)
SCICV (en français), CBCIS (en anglais)
Recruiting
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CIUSSS DE L'ESTRIE – CENTRE HOSP. UNIV. DE SHERBROOKE
HOPITAL FLEURIMONT
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Bladder/urothelial |
Dr. Claudio Jeldres
Elsie Morneau
819-346-1110 poste 12827
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Groupe d'étude en oncologie du Québec