Titre Prophylactic Versus Therapeutic Alpha-Blockers in Prostate Cancer Patients Undergoing Radical Course Radiation Therapy ± HDR Boost.
Protocole ID PCS VII
ClinicalTrials.gov ID NCT02220829
Type(s) de cancer Prostate
Phase Phase III
Institution CIUSSS DU CENTRE-OUEST-DE-L'ILE-DE-MONTREAL
   HOPITAL GENERAL JUIF SIR MORTIMER B.DAVIS
      3755 rue de la Côte Ste. Catherine, Montréal, QC, H3T 1E2
Ville Montréal
Investigateur(trice) principal(e) Dr Tamim Niazi
Coordonnateur(trice) Ashley Feng
 514-340-8222 poste 26510
Statut Fermé
Critètes d'éligibilité
  • Adult male 18 years of age or older
  • Patients with confirmed diagnosis of adenocarcinoma of the prostate.
  • The primary treatment should be external beam radiation therapy (EBRT) with or without high dose rate (HDR) brachytherapy boost.
  • Clinical or radiological diagnosis of T1a - T3b.
  • No limitation with respect to Gleason score.
  • No limitation with respect to total Prostate-specific Antigen (PSA) value.
  • Karnofsky performance score (KPS) of ≥ 70.
Critètes d'exclusion
  • Small cell cancer of the prostate
  • T4 disease, invading bladder or rectum.
  • Adjuvant or salvage radiation therapy
  • Brachy monotherapy
  • KPS < 70