Une étude randomisée de phase II pour évaluer l’efficacité et la sécurité d’un protocole d’escalade de dose de radiation adapté et métaboliquement sélectif pour les patients atteints d’un cancer du poumon non à petites cellules (NSLC) localement avancé qui reçoivent une chimioradiothérapie définitive.
PET-BOOST
NCT02788461
 Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
 SITE GLEN
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Phase II |
Marianna Perna
514-934-1934 poste 43191
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(EN) A Multicenter, Open-label, Phase 1b/2 Study To Evaluate Safety And Efficacy Of Avelumab (msb0010718c) In Combination With Chemotherapy With Or Without Other Anti-cancer Immunotherapies As First-line Treatment In Patients With Advanced Malignancies
B9991023
NCT03317496
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Phase I |
Olivier Bouchereau
514-934-1934 poste 43129
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(EN) Brigatinib in Patients With Anaplastic Lymphoma Kinase-Positive (ALK+), Advanced Non-Small-Cell Lung Cancer (NSCLC) Progressed on Alectinib or Ceritinib
Brigatinib-2002
NCT03535740
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
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(EN) Neoadjuvant Platform Trial in Patients With Surgically Resectable Non-Small Cell Lung Cancer (NSCLC)
IND.242
NCT05714891
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
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(EN) A Randomized, Controlled, Open Label, Phase III Study Evaluating the Efficacy and Safety of JDQ443 Versus Docetaxel in Previously Treated Subjects With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer
KontRASt-02
NCT05132075
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
Sarah Boujan
514-934-1934 poste 34907
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(EN) A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-naïve Subjects With Advanced or Metastatic PD-L1 High (TPS ?50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations
TROPION-Lung08
NCT05215340
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
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(EN) A Single-Arm, Open-Label, Multicenter Phase 2 Study to Evaluate the Efficacy and Safety of Taletrectinib in Patients With Advanced or Metastatic ROS1 Positive NSCLC and Other Solid Tumors
TRUST-II
NCT04919811
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
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(EN) A Phase III, Randomised, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
AVANZAR
NCT05687266
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Nicola Raby
514-934-1934 poste 34095
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(EN) A Phase 3, Randomized Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib Versus Lazertinib as First-Line Treatment in Patients With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer.
MARIPOSA
NCT04487080
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Corneille Bashagaluke
514-934-1934 poste 34907
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(EN) A Randomized, Double-blind, Placebo-controlled, Phase III Study Evaluating the Efficacy and Safety of Canakinumab in Combination With Docetaxel Versus Placebo in Combination With Docetaxel in Adult Subjects With Non-small Cell Lung Cancer (NSCLC) Previously Treated With PD-(L)1 Inhibitors and Platinum-based Chemotherapy
CANOPY 2
NCT03626545
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Corneille Bashagaluke
514-934-1934 poste 34907
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Groupe d'étude en oncologie du Québec