ORL

TITRE Radiothérapie des Cordes Vocales vs. du Larynx Entier pour le Traitement du Cancers Glottiques de Stade Précoce (VOCAL): Une Étude Bayésienne Multicentrique Randomisée de Phase II
PROTOCOLE ID VOCAL
CLINICAL TRIAL.gov ID NCT03759431
TYPE(S) DE CANCER ORL
PHASE Phase II
TYPE D'ÉTUDE Traitement
INSTITUTION CHUM
1051 rue Sanguinet
(514) 890-8000
VILLE Montréal
INVESTIGATEUR(RICE) PRINCIPAL(E) Houda Bahig
COORDONATEUR(RICE) Diane Trudel
diane.dt.trudel.chum@ssss.gouv.qc.ca
514-890-8000 poste 11181
STATUT  Fermé
CRITÈRES D'ÉLIGIBILITÉ (EN)
  • Stage T1a-b N0 of the true vocal cords planned for definitive RT
  • Patient not candidate for laser surgery or declined laser surgery
  • Biopsy-confirmed squamous cell carcinoma, including verrucous carcinoma
  • Eastern Cooperative Oncology Group performance status 0-2
  • Ability to provide written informed consent.
CRITÈRES D'EXCLUSION (EN)
  • Previous irradiation of the head and neck (HNC) region
  • Pregnancy or breastfeeding
  • Any medical condition that represents, in the opinion of the investigator, a contraindication to radiotherapy or would prevent follow-up after radiotherapy.
  • Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 2 years.