Titre The Effect of INPWT on Wound Complications and Clinical Outcomes Following Lower Extremity Sarcoma Surgery in Patients Treated With Preoperative Radiation Therapy: A Multicentre Randomized Controlled Trial
Protocole ID 20170154
ClinicalTrials.gov ID NCT03175718
Type(s) de cancer Sarcome
Phase Autres
Type étude Traitement
      5415 boul. de l'Assomption, Montréal, QC, H1T2M4
Ville Montréal
Investigateur(trice) principal(e) Dr Marc Isler
Coordonnateur(trice) Jany Barry
Statut Actif en recrutement
Critètes d'éligibilité
  • Patients 18 years of age and older and are able to provide written consent.
  • Patients with lower extremity soft tissue sarcoma confirmed by tissue pathology.Each patient must have local cross sectional imaging (CT or MRI) and a staging CT chest.
  • Patients eligible for treatment with preoperative radiation therapy followed by limb salvage surgery.
  • Patients for which a primary closure must be attained at the time of surgery.
  • Patient must be available for postoperative follow-up at the treating center.
Critètes d'exclusion
  • Patients who are less than 18 years of age.
  • Patients with a benign disease or who have had previous surgery or radiation therapy to the affected area.
  • Patients who underwent surgical amputation
  • Patients in which primary closure was not achieved (including free flaps and split thickness skin grafts).
  • Patients with a life expectancy less than 120 days.
  • Patients who have an allergy or sensitivity to adhesive dressings.
  • Other major medical condition preventing safe usage of the INPWT dressing.