Titre The Effect of INPWT on Wound Complications and Clinical Outcomes Following Lower Extremity Sarcoma Surgery in Patients Treated With Preoperative Radiation Therapy: A Multicentre Randomized Controlled Trial
Protocole ID 20170154
ClinicalTrials.gov ID NCT03175718
Type(s) de cancer Sarcome
Phase Autres
Type étude Traitement
Institution CIUSSS DE L'EST-DE-L'ILE-DE-MONTREAL
   PAV. MAISONNEUVE/PAV. MARCEL-LAMOUREUX
      5415 boul. de l'Assomption, Montréal, QC, H1T2M4
Ville Montréal
Investigateur(trice) principal(e) Dr Marc Isler
Coordonnateur(trice) Jany Barry
514-252-3400
Statut Actif en recrutement
Critètes d'éligibilité
  • Patients 18 years of age and older and are able to provide written consent.
  • Patients with lower extremity soft tissue sarcoma confirmed by tissue pathology.Each patient must have local cross sectional imaging (CT or MRI) and a staging CT chest.
  • Patients eligible for treatment with preoperative radiation therapy followed by limb salvage surgery.
  • Patients for which a primary closure must be attained at the time of surgery.
  • Patient must be available for postoperative follow-up at the treating center.
Critètes d'exclusion
  • Patients who are less than 18 years of age.
  • Patients with a benign disease or who have had previous surgery or radiation therapy to the affected area.
  • Patients who underwent surgical amputation
  • Patients in which primary closure was not achieved (including free flaps and split thickness skin grafts).
  • Patients with a life expectancy less than 120 days.
  • Patients who have an allergy or sensitivity to adhesive dressings.
  • Other major medical condition preventing safe usage of the INPWT dressing.