Étude d’augmentation de la dose et d’expansion de la cohorte de phase 1 sur le TSR-042, un anticorps monoclonal anti-PD-1, chez des patients présentant des tumeurs solides avancées
GARNET
NCT02715284
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Phase I |
Phuong-Nam (Nathalie) Nguyen
514-934-1934 poste 31975
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(EN) A Phase II, Multicentre, Open-label, Master Protocol to Evaluate the Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumours
TROPION-PanTumor03
NCT05489211
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Rodrigo Skowronski
514-934-1934 poste 36275
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(EN) A phase 1A/B open-label master study of PF-07799544 as a single-agent and in combination with other targeted agents in participants with advanced solid tumors
C4901001
NCT05538130
Actif en recrutement
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CENTRE UNIVERSITAIRE DE SANTE MCGILL
SITE GLEN
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Abdul-Rahman El-Hassan
514-934-1934 poste 35161
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(EN) A Phase 1b/2, Protocol Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Sotorasib Monotherapy and in Combination With Other Anti-cancer Therapies in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation
20190135 (CodeBreak 101)
NCT04185883
Actif en recrutement
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L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Maryse Gingras
418-691-5781
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(EN) A Multicenter, Randomized, Double-Blind, Phase 2, Basket Study of MK-4280A, a Coformulation of Favezelimab With Pembrolizumab in Selected Solid Tumors
KeyForm-010 (MK-4280A-010)
NCT06036836
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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Maryse Gingras
418-525-4444 poste 67322
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(EN) A phase 1A/B open-label master study of PF-07799544 as a single-agent and in combination with other targeted agents in participants with advanced solid tumors
C4901001
NCT05538130
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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Geneviève Rochette
418-525-4444 poste 67540
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(EN) A Phase 1/2 Study of ALKS 4230 Administered Intravenously as Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
ARTISTRY-1
NCT02799095
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Maryse Gingras
418-691-5781
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(EN) A Phase 2 Basket Study of Disitamab Vedotin in Adult Subjects With Previously Treated, Locally-Advanced Unresectable or Metastatic Solid Tumors That Express HER2
SGNDV-005
NCT06003231
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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Maryse Gingras
418-525-4444 poste 67322
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Étude de phase II, ouverte et multicentrique, évaluant le lenvatinib combiné au pembrolizumab chez des sujets déjà traités pour des tumeurs solides sélectionnées
MK-7902-005 (LEAP-005)
NCT03797326
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
L'HOTEL-DIEU DE QUEBEC ET CRCEO
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Phase II |
Véronique Jobin
418-525-4444 poste 15780
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(EN) A Phase II Study of Durvalumab Treatment Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity Substudy B: For Continued Treatment (=/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies
IND.238
NCT03847649
Actif en recrutement
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CHU DE QUEBEC – UNIVERSITE LAVAL
HOPITAL DE L'ENFANT-JESUS
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