Colorectal

TITRE	Étude de phase II pour évaluer l’innocuité de la prise en charge non chirurgicale du cancer du bas rectum
PROTOCOLE ID	PJT - 148730 (NOM - rectal cancer)
CLINICAL TRIAL.gov ID	NCT03179540
TYPE(S) DE CANCER	Colorectal
PHASE	Phase II
TYPE D'ÉTUDE
INSTITUTION	CHU DE QUEBEC – UNIVERSITE LAVAL 11 Côte du Palais (418) 525-4444
VILLE	Québec
INVESTIGATEUR(RICE) PRINCIPAL(E)	Sébastien Drolet
COORDONATEUR(RICE)	Nicole Chabot nicole.chabot@crchudequebec.ulaval.ca 418-525-4444 poste 53266
STATUT	Actif en recrutement
CRITÈRES D'ÉLIGIBILITÉ	(EN) Completed chemoradiotherapy (CRT) as standard of care [Stage II and Stage III (T3-T4N0, AnyTN1-2)]; [50 Gy (2 Gy x 25 fractions) with 5-FU or capecitabine] Planned or probable APR ALL criteria for complete clinical response are met between 8 and 10 weeks following completion of CRT 18 years or older Provides written consent
CRITÈRES D'EXCLUSION	(EN) Unable to undergo MRI Metastatic disease (including extramesorectal and retroperitoneal lymph nodes) Pregnancy Inflammatory bowel disease More than one primary colorectal cancer Other malignancy within 5 years of treatment for current rectal cancer Unfit for surgery